Creative Biogene is one of the leading biotechnology companies which has the expertise and ability in providing antisense oligonucleotide service for customers worldwide. Creative Biogene's sophisticated equipments, advanced technologies and highly experienced staffs are available to provide you with the comprehensive antisense oligonucleotide service, including antisense oligonucleotide synthesis, ASO in vitro screening service and ASO in vivo testing service. Creative Biogene’s goal is to provide you with the most affordable, high-quality antisense oligonucleotide service to ensure your satisfaction in a timely and professional manner.
Antisense technology is a universal approach for the inhibition of gene expression in a sequence-specific manner. Since the discovery that oligodeoxynucleotides can act as antisense agents that inhibit viral replication in cell culture, antisense technology has been used in knockdown experiments, target validation, drug therapy, and other applications. In antisense technology, antisense oligonucleotide represents an excellent tool to inhibit gene expression levels both in vitro and in vivo. Antisense oligonucleotides (ASOs) are 15–25 nt DNA sequences designed to bind complementary RNA targets, ultimately facilitating their degradation. The discovery of antisense oligonucleotide introduced a new approach to the development of drug therapeutics, offers the potential to develop highly selective and less toxic drugs.