Drug safety and efficacy, the essential issues in drug discovery, are greatly affected by drug metabolism and drug-drug interactions. Since a drug is eliminated either by excretion or by metabolism to one or more active or inactive metabolites after entering the body, the metabolism rate and the bioactivity of the metabolites generated in the elimination process directly affect the retaining time of the drug in the body in bioactive forms. A high metabolism rate and the generation of active metabolites can produce a blood level that causes unacceptable toxicity. Therefore, it is crucial to understand better the metabolizing route of a drug at an early stage of drug development to predict drug toxicity or side effects, drug-drug interactions and obtain information that helps form dosing strategies.
Due to the complexity of the drug development process, you need a flexible partner to provide reliable support to your specific needs. With extensive experience and knowledge in drug development, Creative Bioarray can provide various flexible and integrated services for drug discovery. Our experienced scientific team and state-of-the-art facilities enable us to offer our clients the following benefits: